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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF IP |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:20 - 1:50 |
| Calculated MW | 68kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human ATG16L1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | ch |
| Synonym | IBD10; WDR30; APG16L; ATG16A; ATG16L; |
Western blot analysis of extracts of various cell lines, using ATG16L1 antibody.
Immunohistochemistry analysis of paraffin-embedded human colon cancer using ATG16L1 antibody
Immunofluorescence analysis of A549 cell using ATG16L1 antibody. Blue: DAPI for nuclear staining.
Immunoprecipitation analysis of extracts of HepG2 cells incubated with ATG16L1 antibody.
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
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