ALAD-Phosphorylated Antibodies

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ALAD

Qty


Total
$220
Catalog #
A8398
Antibody Type
Polyclonal Antibody
Gene ID
210
Swiss Prot
P13716
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100
Calculated MW36kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human ALAD
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymPBGS; ALADH;
Images
  • A8398: image 1

    Western blot analysis of extracts of various cells, using ALAD antibody.

  • A8398: image 2

    Immunohistochemistry of paraffin-embedded human gastric using ALAD antibody at dilution of 1:100 (x40 lens).

Background

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.

Protocol

N/A

MSDS
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